Thanks for the suggestions! Here is what I did / found:
there seems to be problems associated with this update, thus I wont update the phone, not worth it.. and this might be my last HTC phone anyways...
Try something else. Settings > Personalize > Home Screen Style, change from Traditional to BlinkFeed followed by apply. Then add a couple screens and set one of them to Home, see if it recognizes Home with BlinkFeed running.
Then, you can switch back to Traditional afterwords. In any case, see if Home works with BlinkFeed running, and see if it corrects itself when you switch back to Traditional.
Thanks again for the suggestions. I tried switching to Blink and again the Home button does not work. Switched bank to Traditional and still doesn't work. The other issue I have and forgot to mention is that the Home screen and other Sense screens don't rotate. Auto rotate is selected and apps rotate fine.
Data and cell connections still don't seem as good as they had been. Still dropping to 3G in areas that previously were 4G and now find areas where cell service drops out completely.